Figure 1.

Sequence analysis of Sc-hep. (A): cDNA and deduced amino acid sequences of the Sc-hep gene. The black underline and the asterisks represent the start and stop codons, respectively. The blue, yellow, and green underlines indicate signal peptide, propeptide, and mature peptide, respectively. The red squares denote the PolyA signal. (B): Analysis of Sc-hep gene structure. (C): Comparison of vertebrate hepcidin gene structure. The boxes, lines, red regions, and purple regions represent exons, introns, 5’-UTR, and 3’-UTR, respectively. The blue, yellow, and green regions represent signal peptides, propeptides, and mature peptides, respectively.