Table 1.

The RMSD^a results (in angstrom) of five different protein–protein docking approaches to reproduce the known IRE1 dimer complexes.

	Face-to-Face Dimer (PDB Code: 3P23)	Back-to-Back Dimer (PDB Code: 4YZC)
SwarmDock	1.39	3.56
ZDOCK	12.48	3.32
HsymDock	3.12	13.25
PatchDock	24.33	29.49
ClusPro	3.58	31.01

^a Root mean square deviation (RMSD) was calculated for Cα atoms by superimposing the top-scored docked pose generated by the program with the crystallographic structures.