Table 1.

Overview about the p.(Gly624Asp) in COL4A5-associated clinical phenotype and the genetic zygosity of the affected family members.

Individual	Zygosity	Current age or age at death	Age at microscopic hematuria	Age at mircoalbuminuria or proteinuria	Age at dialysis	Age at transplantation
III-3	n.d.	89 years; †	n.d.	n.d.	n.d.	n.d.
IV-1	n.d.	75 years; †	n.d.	n.d.	70 years	n.p.
IV-2	n.d.	34 years; †	n.d.	n.d.	33 years	n.d.
IV-3	n.d.	56 years; †	n.d.	n.d.	49 years	56 years
IV-4	heterozygous	78 years	n.d.	n.d.	n.y.	n.y.
IV-4	n.d.	84 years	n.d.	23 years	n.y.	n.y.
IV-8	n.d.	n.d.; †	n.d.	n.d.	n.d.	n.d.
IV-3	homozygous	52 years	20 years	41 years	n.y.	n.y.
VI-3	heterozygous	21 years	6 months	4 years	n.y.	n.y.
VI-4	hemizygous	19 years	1 year 10 months	1 year 10 months	n.y.	n.y.

n.d., no data available; n.p., not performed; n.y., not yet;

^†, deceased.