Table 6.
Group No. | Treatment | Dose (mg/kg/day) | Weight D0 | Weight D4 | Weight Change % |
---|---|---|---|---|---|
Group 1 (negative control) | Vehicle | 0.2 mL | 24.85 ± 0.81 | 21.93 ± 1.32 | −2.87 ± 1.21 |
Group 2 (A100) | Extract | 100 mg/kg | 24.69 ± 1.10 | 24.54 ± 0.87 | −0.15 ± 0.63a4b1d1e1 |
Group 3 (A200) | Extract | 200 mg/kg | 24.27 ± 1.19 | 24.37 ± 0.56 | 0.10 ± 1.03a4b1c1e1 |
Group 4 (A400) | Extract | 400 mg/kg | 24.28 ± 1.09 | 24.46 ± 0.76 | 0.18 ± 0.93a4b1c1d1 |
Group 5 (positive control) | Chloroquine | 10 mg/kg | 24.30 ± 1.28 | 24.38 ± 1.05 | 0.18 ± 0.78 |
* a, compared to negative control; b compared to positive control, c to 100 mg/kg, d to 200 mg/kg, e to 400 mg/kg; 1 P > .05 (not significant), 2 P < .05, 3 P < .01, 4 P < .001.