Table 1.
Patient and tumour characteristics
| No. of patients* (n = 613) | |
|---|---|
| Age (years) † | 61 (52–68) |
| Sex ratio (M : F) | 415 : 198 |
| Distance from anal verge (mm) † | 40 (30–50) |
| Clinical stage | |
| I | 3 (0·5) |
| II | 213 (34·7) |
| III | 397 (64·8) |
| Histological type | |
| Well/moderately differentiated | 568 (92·7) |
| Other | 45 (7·3) |
| (Chemo)radiotherapy regimen | |
| Long course | 520 (84·8) |
| Short course | 93 (15·2) |
| Induction systemic chemotherapy | 94 (15·3) |
| Interval from completion of long‐course CRT to surgery (days) † | 48 (44–53) |
| Interval from completion of short‐course RT to surgery (days) † | 11 (9–17) |
| Operative procedure | |
| Sphincter preserving | 442 (72·1) |
| Sphincter non‐preserving | 171 (27·9) |
| LLND | |
| Overall | 212 (34·6) |
| Unilateral | 176 (83·0) |
| Bilateral | 36 (17·0) |
| Laparoscopic procedure | 575 (93·8) |
| ypT status ‡ | |
| ypT0 | 95 (15·5) |
| ypT1 | 36 (5·9) |
| ypT2 | 179 (29·2) |
| ypT3 | 279 (45·5) |
| ypT4 | 24 (3·9) |
| No. of harvested lymph nodes † | 18 (14–24) |
| R status | |
| R0 | 606 (98·9) |
| R1 | 7 (1·1) |
| Lymphovascular invasion | 333 (54·3) |
| Adjuvant chemotherapy | 292 (47·6) |
*
With percentages in parentheses unless indicated otherwise;
†
values are median (i.q.r.).
‡
Residual tumor depth, according to the AJCC Cancer Staging Manual20. CRT, chemoradiotherapy; RT, radiotherapy; LLND, lateral lymph node dissection.