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. 2019 Sep 27;3(12):1674–1686. doi: 10.1002/hep4.1433

Figure 6.

Figure 6

Effect of a let7a‐5p mimic on endogenous ABCC2 mRNA in Huh‐7 cells. Overexpression of the let7a‐5p mimic but not the miR 223‐3p and miR199b‐3p mimics led to a significant decrease in ABCC2 mRNA levels. In contrast, expression of the miR 223‐3p and miR199b‐3p mimics had no effect on ABCC2 levels. Expression of a let7a‐5p mimic and mimic inhibitor led to an increase in endogenous ABCC2 mRNA levels (Fig. 6B), whereas expression of the miR 223‐3p and miR199b‐3p mimics and inhibitors had no effect on ABCC2 mRNA levels. *P < 0.01.