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Overview of EPS pathogenesis depicting the normal peritoneum on the left and the changes induced during EPS along with the factors that are involved in EPS on the right. CNI: Calcineurin inhibitors; GDP: glucose degradation products; MMT: mesothelial-to-mesenchymal transition; PD: Peritoneal Dialysis; TGF-β1: Transforming Growth Factor β1; VEGF: Vascular Endothelial Growth Factor.
