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. 2019 Nov 8;20(22):5590. doi: 10.3390/ijms20225590
ALK anaplastic lymphoma kinase
BOC tert-butyloxycarbonyl-protecting group
CLSM confocal laser scanning microscopy
c-Met hepatocyte growth factor receptor
COMU (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate
crizotinib (R)-crizotinib, (Xalkori®, Pfizer)
crizotinib* racemic mixture of (R)-crizotinib and (S)-crizotinib
EMEM Eagle’s minimum essential medium
FBS Fetal bovine serum
fibroblast cells human primary human skin fibroblast cells
galectin-1 lectin galactoside binding soluble 1
galectin-3 lectin galactoside binding soluble 3
HRMS high resolution mass spectrometry
LMP lysosomal membrane permeabilization
MJ55* racemic mixture of (R)-MJ55 and (S)-MJ55
NSCLC non-small cell lung cancer
Pd(dppf)Cl2 [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium(II)
ROS-1 ROS proto-oncogene 1, receptor tyrosine kinase
RTK receptor tyrosine kinase
SD standard deviation
TEA triethylamine
TFEB transcription factor EB
THF tetrahydrofuran