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. 2019 Dec 2;2019(12):CD003531. doi: 10.1002/14651858.CD003531.pub4

Jarvis 2006.

Methods Randomised, cross‐over study. Statistical analysis methods unclear but paired data obtained via correspondence
Participants N = 20 participants
Inclusion criteria: diagnosed with OSA; established on CPAP therapy
Interventions Modified APAP (bi‐level pressure mode) versus fixed CPAP
Study duration: 2 x 2 weeks
Outcomes
  1. Machine usage (average hours used)

  2. AHI

  3. Treatment pressure

  4. Preference

Funding & conflicts of interest statements Resmed sponsored the study but no other details were available.
Notes TJL emailed for confirmation of data and methods 5 September 2008. Reply from Resmed October 2008
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Quote: "The study was randomised by pulling the order of treatment received 'out of a hat'"
Allocation concealment (selection bias) Low risk Quote: "The person who pulled the order was a ResMed employee independent of the study and with no knowledge of the study."
Blinding of participants and personnel (performance bias) 
 Machine usage, symptoms, quality of life, withdrawal, adverse effects Unclear risk Information not available
Blinding of participants and personnel (performance bias) 
 AHI, blood pressure, treatment pressure Low risk These outcomes unlikely to be affected by awareness of treatment group.
Blinding of outcome assessment (detection bias) 
 Machine usage, symptoms, quality of life, withdrawal, adverse effects Unclear risk Information not available
Blinding of outcome assessment (detection bias) 
 AHI, blood pressure, treatment pressure Low risk These outcomes unlikely to be affected by awareness of treatment group.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All completed
Selective reporting (reporting bias) Low risk All outcomes reported
Other bias Low risk No concerns identified