Jarvis 2006.
Methods | Randomised, cross‐over study. Statistical analysis methods unclear but paired data obtained via correspondence | |
Participants | N = 20 participants Inclusion criteria: diagnosed with OSA; established on CPAP therapy |
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Interventions | Modified APAP (bi‐level pressure mode) versus fixed CPAP Study duration: 2 x 2 weeks |
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Outcomes |
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Funding & conflicts of interest statements | Resmed sponsored the study but no other details were available. | |
Notes | TJL emailed for confirmation of data and methods 5 September 2008. Reply from Resmed October 2008 | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Quote: "The study was randomised by pulling the order of treatment received 'out of a hat'" |
Allocation concealment (selection bias) | Low risk | Quote: "The person who pulled the order was a ResMed employee independent of the study and with no knowledge of the study." |
Blinding of participants and personnel (performance bias) Machine usage, symptoms, quality of life, withdrawal, adverse effects | Unclear risk | Information not available |
Blinding of participants and personnel (performance bias) AHI, blood pressure, treatment pressure | Low risk | These outcomes unlikely to be affected by awareness of treatment group. |
Blinding of outcome assessment (detection bias) Machine usage, symptoms, quality of life, withdrawal, adverse effects | Unclear risk | Information not available |
Blinding of outcome assessment (detection bias) AHI, blood pressure, treatment pressure | Low risk | These outcomes unlikely to be affected by awareness of treatment group. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | All completed |
Selective reporting (reporting bias) | Low risk | All outcomes reported |
Other bias | Low risk | No concerns identified |