Loube 2004.

Methods	Randomised study. Design and method of randomisation not reported. Single‐blind trial
Participants	N = 16 participants. Distribution and baseline details not reported Inclusion criteria: participants with newly diagnosed CPAP; AHI > 15; uncomplicated CPAP lab PSG Exclusion criteria: REM‐related/supine positional OSA
Interventions	C‐Flex PAP versus fixed pressure CPAP Study duration: 4 weeks
Outcomes	Machine usage Symptoms (ESS) Quality of life (FOSQ)
Funding & conflicts of interest statements	Not available (conference abstract)
Notes	Unpublished conference abstract. Details requested by email
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Information not available; requested
Allocation concealment (selection bias)	Unclear risk	Information not available; requested
Blinding of participants and personnel (performance bias) Machine usage, symptoms, quality of life, withdrawal, adverse effects	Unclear risk	Information not available
Blinding of participants and personnel (performance bias) AHI, blood pressure, treatment pressure	Unclear risk	Information not available
Blinding of outcome assessment (detection bias) Machine usage, symptoms, quality of life, withdrawal, adverse effects	Unclear risk	Information not available
Blinding of outcome assessment (detection bias) AHI, blood pressure, treatment pressure	Unclear risk	Information not available
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Information not available; requested
Selective reporting (reporting bias)	Unclear risk	Information not available
Other bias	Unclear risk	Information not available