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. 2019 Dec 2;2019(12):CD003531. doi: 10.1002/14651858.CD003531.pub4

Meurice 1996.

Methods Randomised, parallel group study. Statistical analysis based on t tests but unadjusted data presented for all outcomes.
Participants N = 16 participants (16 M). Mean age: 54; BMI: 34.2 kg/m2; AHI: 43.6; ESS: 14.8
Inclusion criteria: diagnosis of OSA (confirmed by polysomnography; untreated OSA)
Exclusion criteria: not reported
Interventions Auto‐CPAP versus fixed CPAP
Study duration: 3 weeks
Outcomes
  1. Machine usage (average hours used)

  2. AHI

  3. Symptoms (ESS)

  4. Withdrawals

Funding & conflicts of interest statements Not provided
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Random numbers table
Allocation concealment (selection bias) Unclear risk Information not available
Blinding of participants and personnel (performance bias) 
 Machine usage, symptoms, quality of life, withdrawal, adverse effects Low risk Participants unaware as to group they were randomised to (CPAP machines were identical).
Blinding of participants and personnel (performance bias) 
 AHI, blood pressure, treatment pressure Low risk These outcomes unlikely to be affected by awareness of treatment group.
Blinding of outcome assessment (detection bias) 
 Machine usage, symptoms, quality of life, withdrawal, adverse effects Low risk Participants unaware as to group they were randomised to (CPAP machines were identical).
Blinding of outcome assessment (detection bias) 
 AHI, blood pressure, treatment pressure Low risk These outcomes unlikely to be affected by awareness of treatment group.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All participants completed the study
Selective reporting (reporting bias) Unclear risk Information not available
Other bias Low risk No concerns identified