Meurice 2007.
Methods | Randomised, multicentre, parallel group trial | |
Participants | N = 83. Mean age: 56 years; AHI: 52; ESS: 11.5 Inclusion criteria: new diagnosis of OSA; CPAP‐naive; AHI > 30 |
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Interventions | Four auto‐CPAP machines assessed:
All 4 compared against fixed pressure CPAP Study duration: 24 weeks |
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Outcomes |
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Funding & conflicts of interest statements | Not provided | |
Notes | Data aggregated from 4 auto‐CPAP groups | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Quote: "The randomisation was carried out centrally..." |
Allocation concealment (selection bias) | Low risk | Quote: "...randomly coded envelopes opened by a coordinator from envelopes batched for each centre in order to have similar proportions of patients in each group from each centre." |
Blinding of participants and personnel (performance bias) Machine usage, symptoms, quality of life, withdrawal, adverse effects | Unclear risk | Information not available |
Blinding of participants and personnel (performance bias) AHI, blood pressure, treatment pressure | Low risk | These outcomes unlikely to be affected by awareness of treatment group. |
Blinding of outcome assessment (detection bias) Machine usage, symptoms, quality of life, withdrawal, adverse effects | Unclear risk | Information not available |
Blinding of outcome assessment (detection bias) AHI, blood pressure, treatment pressure | Low risk | These outcomes unlikely to be affected by awareness of treatment group. |
Incomplete outcome data (attrition bias) All outcomes | High risk | Participants who withdrew were not included in the analysis |
Selective reporting (reporting bias) | Unclear risk | Information not available |
Other bias | Low risk | No concerns identified |