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. 2019 Nov 18;20(22):5791. doi: 10.3390/ijms20225791

Table 2.

Initial and maintenance therapeutic regimens.

Treatment Regimens
Initial, n (%)
Bevacizumab-mFOLFOX6 22 (48%)
Bevacizumab-FOLFIRI 13 (28%)
Bevacizumab-CapOX 2 (4%)
Bevacizumab-CapIRI 9 (20%)
Maintenance, n (%)
Bevacizumab-mFOLFOX6 4 (9%)
Bevacizumab-FOLFIRI 5 (10%)
Bevacizumab-CapIRI 9 (20%)
Bevacizumab-De Gramont 11 (24%)
Bevacizumab-Capecitabine 3 (7%)
Bevacizumab monotherapy 14 (30%)

Bevacizumab-mFOLFOX6 (bevacizumab 5 mg/kg, oxaliplatin 85 mg/m2, folinic acid 400 mg/m2, fluorouracil 400 mg/m2 bolus, fluorouracil 2400 mg/m2 over 46 h every 2 weeks), Bevacizumab-FOLFIRI (bevacizumab 5 mg/kg, irinotecan 180 mg/m2, folinic acid 400 mg/m2, fluorouracil 400 mg/m2 bolus, fluorouracil 2400 mg/m2 over 46 h every 2 weeks), Bevacizumab-CapOX (bevacizumab 7.5 mg/kg on Day 1, oxaliplatin 130 mg/m2 on d1, capecitabine 1000 mg/m2/12 h Days 1–14 every 3 weeks), Bevacizumab-CapIRI (bevacizumab 7.5 mg/kg on Day 1, irenotecan 250 mg/m2 on d1, capecitabine 1000 mg/m2/12 h Days 1–14 every 3 weeks), Bevacizumab-De Gramont (bevacizumab 5 mg/kg, folinic acid 200 mg/m2 on Days 1,2, fluorouracil 400 mg/m2 bolus on Days 1,2, fluorouracil 2400 mg/m2 over 22 h on Days 1,2 every 2 weeks), Bevacizumab-Capecitabine (bevacizumab 7.5 mg/kg on Day 1, capecitabine 1000 mg/m2/12 h Days 1–14 every 3 weeks), Bevacizumab monotherapy (5 mg/kg every 2 weeks or 7.5 mg/kg every 3 weeks).