Table IV.
Univariate and multivariate analyses of overall survival in patients with colorectal cancer.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Variable | HR | 95% CI | P-value | HR | 95% CI | P-value |
| MIR100HG | 3.241 | 2.843–7.231 | <0.001 | 3.533 | 1.877–5.958 | <0.001 |
| Age | 1.072 | 0.694–2.017 | 0.442 | – | – | – |
| Sex | 1.128 | 0.911–1.333 | 0.526 | – | – | – |
| Tumor size | 0.987 | 0.733–2.142 | 0.083 | – | – | – |
| Location | 1.035 | 0.767–1.842 | 0.723 | – | – | – |
| AJCC Stage | 3.951 | 2.523–5.015 | <0.001 | 4.017 | 2.349–3.483 | <0.001 |
| T classification | 1.212 | 1.017–2.335 | 0.047a | 2.012 | 1.954–2.874 | 0.031a |
| N classification | 1.537 | 1.061–4.938 | 0.043a | 1.977 | 1.575–3.213 | 0.044a |
| M classification | 3.596 | 2.427–4.938 | <0.001 | 3.672 | 2.731–5.376 | <0.001 |
| Differentiation | 2.017 | 1.029–3.240 | 0.033a | 1.996 | 1.233–2.841 | 0.042a |
| Vascular invasion | 1.282 | 1.134–2.047 | 0.097 | – | – | – |
a
P<0.05 indicates that the 95% CI of the HR did not include 1. AJCC, American Joint Committee on Cancer; HR, hazard ratio; MIR100HG, mir-100-let-7a-2-mir-125b-1 cluster host gene.