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. 2019 Nov 7;12(1):3–8. doi: 10.3892/mco.2019.1946

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Copyright: © Ponti et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — IHC of primary melanoma. When compared with MLH1, PMS2 and MSH2 levels, an exclusive loss of MSH6 expression was exhibited in a female case of subungual melanoma form the patient cohort, as determined via IHC. In the remaining cases of cutaneous melanoma, the expressions of MLH1, PMS2, MSH2 and MSH6 were within the normal range (scale bars, 100 µm). IHC, immunohistochemistry; MLH1, clone M1 Ventana; PMS2, clone EPR3947 Ventana; MSH2, clone G219-1129; MSH6, clone 44 Ventana; H&E, hematoxylin and eosin.