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. 2019 Nov 12;20(22):5668. doi: 10.3390/ijms20225668

Table 2.

Effects of SGLT2 inhibitors on renaldysfunction.

Empagliflozin Canagliflozin Dapagliflozin
Composite of renal worsening
end-stage renal disease, and renal death Sinificantlydesirerable Sinificantlydesirerable Sinificantlydesirerable
Progression of macroalbuminuria Sinificantly desirerable Sinificantly desirerable N.A.
new onset of microalbuminuria Sinificantly desirerable Sinificantly desirerable N.A.
new onset of microalbuminuria Sinificantly desirerable Sinificantly desirerable N.A.
occurrence of ESKD Sinificantly desirerable Sinificantly desirerable N.A.
reduction of UACR N.A. Sinificantly desirerable Sinificantly desirerable
reduction of eGFR Sinificantlydesirerable Sinificantlydesirerable Sinificantly desirerable
Reference 34 35, 36 37

N.A.: not available; ESKD: endsatgekidney disease; UACR: albumin(mg)-to-creatinine (g) ratio; eGFR: estimatedglomerular filtration rate.