Table 2.
Empagliflozin | Canagliflozin | Dapagliflozin | |
---|---|---|---|
Composite of renal worsening | |||
end-stage renal disease, and renal death | Sinificantlydesirerable | Sinificantlydesirerable | Sinificantlydesirerable |
Progression of macroalbuminuria | Sinificantly desirerable | Sinificantly desirerable | N.A. |
new onset of microalbuminuria | Sinificantly desirerable | Sinificantly desirerable | N.A. |
new onset of microalbuminuria | Sinificantly desirerable | Sinificantly desirerable | N.A. |
occurrence of ESKD | Sinificantly desirerable | Sinificantly desirerable | N.A. |
reduction of UACR | N.A. | Sinificantly desirerable | Sinificantly desirerable |
reduction of eGFR | Sinificantlydesirerable | Sinificantlydesirerable | Sinificantly desirerable |
Reference | 34 | 35, 36 | 37 |
N.A.: not available; ESKD: endsatgekidney disease; UACR: albumin(mg)-to-creatinine (g) ratio; eGFR: estimatedglomerular filtration rate.