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. 2019 Nov 15;20(22):5742. doi: 10.3390/ijms20225742

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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miR-29a precursor treatment improvement of shoulder injury. Schematic drawings for miR-29a precursor treatment for shoulder injury (A). miR-29a expression was increased at 1 week upon miR-29a precursor treatment (B). Echogenicity of injured shoulder was compromised upon miR-29a precursor treatment (C). Tenotomy-mediated irregular footprint (D) along with stand time, maximum contact area, footprint length, and footprint area (E) were improved upon miR-29a precursor treatment. Data are expressed as mean ± SEM from 5–6 mice. Asterisks * (p < 0.05) indicate significant difference between groups analyzed using ANOVA test and Bonferroni post-hoc test. A, acromion; G, glenoid; H, humeral head; Op, tenotomy surgery; RF, right forelimb; LF, left forelimb; NS, not significant.