Table 1.
Diagnosis | Requirements | Category |
---|---|---|
Initial Episode of ARF | Chorea, or 2 major or 1 major and 2 minor manifestations plus evidence of a preceding GAS infection * | Definite ARF |
Initial Episode of ARF | 1 major and 2 minor with the inclusion of evidence of a preceding GAS infection* as a minor manifestation (Jones, 1956) | Probable ARF |
Initial Episode of ARF | Strong clinical suspicion of ARF, but insufficient signs and symptoms to fulfil diagnosis of definite or probable ARF | Possible ARF |
Recurrent ARF | ARF in a case with known past history of ARF or RHD | Recurrent ARF (not eligible for study) |
From NZ Guidelines for Rheumatic Fever 2014 [212]. Major manifestations: Carditis (including evidence of subclinical valvulitis/carditis on echocardiogram), Polyarthritis or aseptic monoarthritis (with or without a history of NSAID use), Chorea (can be stand-alone for ARF diagnosis), Erythema marginatum, Subcutaneous nodules. Minor manifestations: Fever, Raised ESR or CRP, Polyarthralgia, Prolonged P-R interval on ECG. * Elevated or rising antistreptolysin O or other streptococcal antibody is sufficient for a diagnosis of definite ARF. A positive throat culture or rapid antigen test for GAS alone is less secure as 50% of those with a positive throat culture will be carriers only. Therefore, a positive culture alone demotes a case to probable or possible ARF.