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. 2019 Nov 6;20(22):5526. doi: 10.3390/ijms20225526

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Knockdown of miR-221/AEG-1 modulates apoptosis and autophagy regulatory proteins level in HCC cell lines. miR-221 and AEG-1 regulatory protein expressions in miR-221 mimic, miR-221 Inhibitor, AEG-1 siRNA, and their corresponding controls transfected HepG2 (A), Huh7 (B), and Hep3B(C) cells analyzed by Western blot with β-actin used as the internal control. Error bars are presented as the mean ± s.d. and p-values are presented as * p < 0.05, ** p < 0.01,*** p < 0.001,**** p < 0.0001. ns: non-significant compared to the control group.