15-LO |
15-Lipoxygenase |
4E-BP1 |
Eukaryotic translation initiation factor 4E-binding protein 1 |
A-loop |
Activation-loop |
AA |
Arachidonic acid |
ABC |
ATP-binding cassette |
ABCB1/MCR1 |
Multidrug resistance protein 1/Permeability glycoprotein |
ABCC1/MRP1 |
Multidrug resistance-associated protein 1 |
ABCG2/BCRP |
ATP-binding cassette super-family G member 2 |
AKT/PKB |
Protein kinase B |
AML |
Acute Myeloid Leukemia |
AMP |
Adenosine Monophosphate |
AMPK |
AMP-activated protein kinase |
AP |
Adenomatous Polyposis Coli |
Ara-C |
Cytarabine |
ATG |
Autophagy related genes |
ATP |
Adenosine Tri-Phosphate |
AXL |
Tyrosine-protein kinase receptor UFO |
BCL-2 |
B-cell lymphoma 2 |
BCL6 |
B-cell lymphoma 6 |
Bcl-xL |
B-cell lymphoma-extra large |
BCR-ABL |
Breakpoint Cluster Region-Abelson murine leukemia viral oncogene homolog 1 |
BET |
Bromodomain Extra-Terminal motif |
BH3 |
Bcl-2 homology domain 3 |
BIM |
Bcl-2-like protein 11 |
BLT2 |
Leukotriene B4 receptor 2 |
BM |
Bone Marrow |
BMI1 |
B cell-specific Moloney murine leukemia virus integration site 1 |
BMM |
Bone marrow microenvironment |
BMP |
Bone morphogenetic proteins |
BP-CML |
Blastic phase chronic myeloid leukemia |
c-ABL |
Abelson murine leukemia viral oncogene homolog 1 |
C/EBPβ |
CCAAT/Enhancer-binding Protein beta |
CBL |
Casitas B-lineage Lymphoma |
CCNG2 |
Cyclin G2 |
CCR |
Complete Cytogenetic Remission |
CHR |
Complete Hematological Remission |
CITED2 |
Cbp/p300-interacting transactivator 2 |
CpN |
Cyclophilin |
CML |
Chronic Myeloid Leukemia |
CQ |
Chloroquine |
CRK |
CT10 Regulator of Kinase |
CRKL |
Crk-like protein |
CsA |
Cyclosporine |
CXCL12 |
C-X-C motif chemokine 12 |
CXCR4 |
C-X-C chemokine receptor type 4 |
Cyt |
Cytokines |
CytR |
Cytokine receptors |
DNA |
Deoxyribonucleic acid |
DVL |
Dishevelled |
ECAR |
Extracellular Acidification Rate |
EIF4E |
Eukaryotic translation initiation factor 4E |
ERK |
Extracellular signal-regulated kinases |
ETC |
Electron Transport Chain |
EZH2 |
Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit |
FOXO |
Forkhead box protein O |
GAB2 |
GRB2-associated-binding protein 2 |
GAS6 |
Growth arrest–specific 6 |
GLI1 |
Glioma-associated oncogene homologue 1 |
GRB2 |
Growth factor receptor-bound protein 2 |
GSK-3β |
Glycogen Synthase Kinase 3 Beta |
H3K27me3 |
Histone H3 trimethylase activity at lysine 27 |
HCQ |
Hydroxychloroquine |
HIF-2α |
Hypoxia-inducible factor-2 alpha |
HDAC |
Histone deacetylase |
HSC |
Hematopoietic Stem Cell |
IFN |
Interferon |
IL |
Interleukin |
ILR |
Interleukin Receptor |
JAK |
Janus-family tyrosine kinase |
LC3 |
microtubule-associated protein 1 light chain 3 |
LIC |
Leukemia-Initiating Cells |
LRP5/6 |
Low density lipoprotein receptor-related protein 5/6 |
LSC |
Leukemic Stem Cell |
LT |
Leukotriene |
LTB4 |
Leukotriene B4 |
MCL-1 |
induced myeloid leukemia cell differentiation protein |
MCR |
Major Cytogenetic Remission |
MDR |
Multidrug Resistance |
MDM2 |
Mouse double minute 2 homolog |
MEK |
Mitogen-activated protein kinase kinase; |
MHC |
Major histocompability complex |
miRNA |
Micro ribo nucleic acid; |
MNK |
MAP kinase-interacting serine/threonine-protein kinase |
MPT |
Mitochondrial protein translation |
mTOR |
mechanistic Target Of Rapamycin |
NFAT |
Nuclear factor of activated T-cells |
NSG (NOD/SCID) |
Nonobese diabetic/severe combined immunodeficient |
OCR |
Oxygen Consumption Rate |
P-loop |
Phosphate-binding loop |
PAK1 |
Serine/threonine-protein kinase 1 |
PD-1 |
Programmed cell death 1 |
PD-L1 |
Programmed death-ligand 1 |
PGC-1α |
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha |
PI3K-III |
Phosphoinositide 3-kinase class III |
PORCN |
Porcupine O-acyltransferase |
PPARγ |
Peroxisome proliferator-activated receptor gamma |
PRC |
Protein regulator of cytokinesis |
PTCH |
Protein patched homolog 1 |
RAF |
Rapidly accelerated fibrosarcoma kinases |
RPS6 |
Ribosomal protein S6 |
SH2/SH3 |
SRC Homology 2/3 Domain |
SHC |
SH2-contaltining collagen-related proteins |
SHH |
Sonic Hedgehog |
SIRT1 |
Sirtuin 1 |
SMO |
Smoothened |
SOS |
Son Of Sevenless guanine nucleotide exchange factor |
STAT |
Signal transducer and activator of transcription; |
TCR |
T cell receptor |
TGF-β1 |
Transforming growth factor beta 1 |
TGF-βR |
abrogated transforming growth factor beta receptor |
TKI |
Tyrosine Kinase Inhibitor |
TNF |
Tumor Necrosis Factor |
Ub |
Ubiquitin |
ULK1 |
unc-51 like autophagy activating kinase 1 |
VEGF |
Vascular endothelial growth factor |
VEGFR |
Vascular endothelial growth factor receptor |
WNT |
Wingless-related integration site |