Figure 6.
Proteomic analysis of myoblasts with and without the (CTG)2600 repeat. Volcano plot showing global changes in protein abundance in cells with a (CTG)2600 repeat. The log2 fold change is represented on the x-axis. The y-axis shows the -log10 of the p-value. A p-value of 0.05 and a fold change of 1.5 are indicated by the black dashed lines. All 5838 proteins detected in the eight cell lines are plotted. Each circle represents one protein. Proteins significantly and > 1.5-fold less abundant in cell lines with the (CTG)2600 repeat are shown in blue, and all proteins significantly and > 1.5-fold more abundant are shown in red.