Figure 4.

Immune-related gene sets have enriched expression in RNA editing-high tumors. Shown are examples of ridgeline plots of gene set variation analysis (GSVA) scores of RNA editing-high and -low tumors for (a) six immune-related gene sets and (b) five other gene sets of Molecular Signatures Database (MSigDB) Hallmark collection. Fold change (FC) values comparing scores of editing-high and -low tumors and false discovery rate (FDR) values in significance analysis of the comparisons were calculated with a Bayes-moderated t-test. EMT, epithelial mesenchymal transition.