Figure 2.

Effect of donor concentration on the transport of ³H-Quinidine in Caco-2 cells. Apparent permeability was measured in two directions, (a) absorptive apical-to-basal (a→b) and (b) secretory basal-to-apical (b→a) at various donor concentrations (0.005–100µM). (c) Permeability ratio of quinidine was calculated. Data are represented as means ± s.e.m (n = 3).