Table 2.
Manifestations of TSC. TSC is a spectrum disorder that presents with various symptoms in each single patient [92,93]. The table lists the incidence of each manifestation.
| Organ | Manifestation | Incidence in TSC Patients |
|---|---|---|
| Brain | Epilepsy | 90% |
| SEGA | 10–15% | |
| Autism | 40% | |
| TAND | 90% | |
| Heart | Cardiac rhabdomyoma | 90% in infants 20% in adults |
| Eyes | Retinal hamartoma | 50% |
| Kidney | Angiomyolipoma | 70% |
| Cysts | 35% | |
| Renal cell carcinoma | 2–3% | |
| Lung | Lymphangioleiomyomatosis (LAM) | 30–40% of women |
| Skin | Angiofibroma | 75% |
| Ungual fibroma | 80% | |
| Fibrous cephalic plaques | 25% | |
| Shagreen patches | 50% |