Table 3.
The ascorbic/dehydroascorbic acid ratio (AA/DHA, % of sham) in serum, liver, adrenal gland, and kidney, as well as adrenal noradrenaline (NA) and adrenaline (AD) content (µg/mg tissue). Group categories abbreviations: S—sham operated rat group; S + M—sham operated + meldonium rat group; I/R—ischemia/reperfusion rat group; I/R + M—ischemia/reperfusion + meldonium rat group. Number of animals per experimental group: n = 8. The data are given as mean ± standard error. Minimal significant level: p < 0.05. Significantly different: a in respect to S; b in respect to S + M; c in respect to I/R group.
| Experiment Groups | S | S + M | I/R | I/R + M |
|---|---|---|---|---|
| Kidney AA/DHA | 100.00 ± 8.76 | 134.93 ± 7.48 a | 64.97 ± 6.77 ab | 138.73 ± 7.83 ac |
| Liver AA/DHA | 100.00 ± 8.57 | 181.28 ± 12.15 a | 71.51 ± 6.64 ab | 124.60 ± 10.12 bc |
| Serum AA/DHA | 100.00 ± 4.44 | 197.26 ± 17.02 a | 59.99 ± 3.37 ab | 91.81 ± 7.25 bc |
| Adrenal AA/DHA | 100.00 ± 5.60 | 309.07 ± 12.97 a | 69.12 ± 4.83 ab | 221.09 ± 12.95 abc |
| Adrenal NA | 0.340 ± 0.011 | 2.185 ± 0.105 a | 0.155 ± 0.01 ab | 0.462 ± 0.029 abc |
| Adrenal AD | 1.244 ± 0.228 | 1.068 ± 0.147 | 1.485 ± 0.346 | 1.115 ± 0.238 |