Table 2.
Yields of nanosize biodamage (mDSB) induced by radiation in the control and NP-loaded samples. Amplification factors (AFs) of mono- and bimetallic NPs and the contribution of water-mediated effect (OH effect).
| Sample | mDSB (×10−5) (Breaks Per Plasmid Per Gy) |
AFDSB (%) | OH Effect (%) |
|---|---|---|---|
| Control | 17.47 ± 0.51 | - | - |
| Au-PEG NPs | 23.49±0.94 | 34 ± 2 | - |
| Au:Pt-PEG NPs | 33.18 ± 0.54 | 90 ± 2 | - |
| Control + DMSO | 2.91 ±0.22 | - | 83 ± 1 |
| Au-PEG NPs + DMSO | 3.56 ± 0.13 | 22 ± 4 | 85 ± 1 |
| Au:Pt-PEGNPs + DMSO | 4.14 ± 0.36 | 42 ± 2 | 86 ± 1 |