A role of CD151 in the formation of basal/stem cell-derived mammary tumors in the MMTV-Wnt1 mosaic model. A Images of IHC staining of basal/stem cell-oriented molecular markers in mammary tumors, CK5, CK14 and p63 gene. Staining tumors from the Cd151-wildtype: a, c, e .g and i.; CD151-null tumors; b, d, f, h and j. B Effect of Cd151 deletion on the RAS/MAPK pathway. Levels of total, phosphorylated Erk1/3 adnp38 from individual tumors (n = 4) were analyzed by immunoblotting. Scale bar: 50 μm.