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. 2019 Dec 3;9:15262. doi: 10.1038/s41598-019-51622-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Cytotoxic activity of extracts from potentially novel Streptomyces isolates against colon cancer cell lines. The measurement of cell viability was done using MTT assay and the concentration of extract was 400 µg/mL. The graphs show cytotoxicity effect of the extracts against: (A) HCT-116, (B) Caco-2, (C) SW480, and (D) HT-29. All data are expressed as mean ± standard deviation and significance level are set as 0.05. Symbol (*) indicates p < 0.05 significant difference between the cells treated with extract and control (without extract).