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Effects of SAR502250 and diazepam in the mouse defense test battery on (A), locomotor activity prior to the exposure to the threat; (B), flight response in response to the approaching rat; (C), risk assessment when the rat was chasing the mouse, and (D), defensive attack reactions upon forced contact with the rat. The vehicle or the drugs were administered 60 minutes prior to testing. Data represent mean + SEM, *P < 0.05 and ***P < 0.001. N = 8–11 mice per group.
