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. 2019 Dec 2;11:174. doi: 10.1186/s13148-019-0776-0

Table 1.

Definitions of epigenetics ranging from classical to the translational

Classical Alterations in biological phenotype without an underlying change in genotype
Biological Regulation of eukaryotic gene expression through chromatin remodelling
Chemical Reversible structural modifications of DNA and histone proteins
Drug discovery Targeting proteins that introduce, recognise, or remove DNA and histone modifications