Table 3:
Odds ratio (95% Confidence Interval) of cognitive impairment according to intakes of soy products
| Quartiles of dairy intake |
P for trend* |
||||
|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | ||
| Tofu equivalent | |||||
| Median intake, g/d | 39.4 (18.5-53.0) | 81.1 (73.0-89.3) | 116 (107-128) | 190 (162-241) | |
| Cases/non-cases | 587/3502 | 591/3439 | 640/3624 | 625/3940 | |
| Model 1† | 1.00 | 0.94 (0.82-1.07) | 0.97 (0.85-1.10) | 0.90 (0.79-1.03) | 0.16 |
| Model 2‡ | 1.00 | 0.97 (0.85-1.11) | 0.99 (0.87-1.13) | 0.91 (0.80-1.04) | 0.19 |
| Model 3§ | 1.00 | 1.01 (0.88-1.16) | 1.06 (0.93-1.22) | 0.99 (0.87-1.14) | 0.92 |
| Model 4** | 1.00 | 0.98 (0.86-1.12) | 1.02 (0.89-1.16) | 0.95 (0.83-1.09) | 0.48 |
| Isoflavones | |||||
| Median intake, mg/d | 6.06 (2.58-8.23) | 13.1 (11.6-14.5) | 19.3 (17.5-21.3) | 32.4 (27.2-41.9) | |
| Cases/non-cases | 591/3482 | 599/3437 | 619/3696 | 634/3890 | |
| Model 1† | 1.00 | 0.92 (0.81-1.05) | 0.90 (0.79-1.02) | 0.91 (0.80-1.03) | 0.18 |
| Model 2‡ | 1.00 | 0.95 (0.83-1.08) | 0.93 (0.81-1.06) | 0.92 (0.81-1.05) | 0.24 |
| Model 3§ | 1.00 | 0.99 (0.87-1.14) | 0.99 (0.86-1.13) | 1.01 (0.88-1.15) | 0.90 |
| Model 4** | 1.00 | 0.96 (0.84-1.10) | 0.95 (0.83-1.08) | 0.95 (0.83-1.09) | 0.56 |
| Soy protein | |||||
| Median intake, g/d | 2.15 (1.04-2.85) | 4.33 (3.89-4.75) | 6.17 (5.65-6.72) | 10.0 (8.50- 12.5) | |
| Cases/non-cases | 571/3514 | 603/3437 | 655/3622 | 614/3932 | |
| Model 1† | 1.00 | 0.98 (0.86-1.12) | 1.02 (0.90-1.16) | 0.91 (0.80-1.04) | 0.16 |
| Model 2‡ | 1.00 | 1.01 (0.88-1.15) | 1.06 (0.92-1.21) | 0.92 (0.81-1.05) | 0.18 |
| Model 3§ | 1.00 | 1.06 (0.92-1.21) | 1.13 (0.99-1.30) | 1.00 (0.87-1.15) | 0.87 |
| Model 4** | 1.00 | 1.02 (0.89-1.17) | 1.08 (0.95-1.24) | 0.96 (0.83-1.10) | 0.50 |
Linear trend was tested by treating the median values of quartiles or frequency of milk intake as a continuous variable
Multivariable model 1: adjusted for age, sex, dialect, year of interview, educational level, and marriage status;
Multivariable model 2: further adjusted for body mass index, physical activity, smoking status, alcohol use, baseline history of self-reported hypertension, diabetes, heart attack, and stroke, history of cancer, sleep status, and total energy intake;
Multivariable model 3: further adjusted for dairy, red meat, poultry, fish, vegetables, fruits, tea, coffee, and soda;
Multivariable model 4: model 2 plus vegetable-fruit-soy (VFS) dietary pattern.