Table 4:

Odds ratio (95% Confidence Interval) of cognitive impairment according to intakes of calcium

	Quartiles of calcium intake				P for Trend*
	Q1	Q2	Q3	Q4
Dietary calcium
Median intake, mg/d	257	339	412	598
Cases/non-cases	609/3,427	593/3,352	602/3,787	639/3,939
Model 1†	1.00	0.86 (0.76-0.98)	0.81 (0.71-0.92)	0.78 (0.69-0.89)	0.001
Model 2‡	1.00	0.88 (0.77-1.01)	0.82 (0.72-0.93)	0.80 (0.70-0.91)	0.002
Model 3**	1.00	0.92 (0.80-1.06)	0.86 (0.75-1.00)	0.84 (0.72-0.97)	0.03
Model 4††	1.00	0.89 (0.78-1.02)	0.83 (0.72-0.96)	0.81 (0.71-0.93)	0.007
Dairy calcium
Median intake, mg/d	7.2	45.7	101	314
Cases/non-cases	626/3,717	624/3,478	588/3,575	605/3,735
Model 1†	1.00	0.97 (0.85-1.10)	0.90 (0.79-1.02)	0.84 (0.74-0.95)	0.005
Model 2‡	1.00	1.01 (0.88-1.15)	0.93 (0.82-1.07)	0.87 (0.76-0.99)	0.01
Model 3**	1.00	1.02 (0.89-1.16)	0.94 (0.83-1.08)	0.86 (0.75-0.98)	0.008
Model 4††	1.00	1.00 (0.88-1.15)	0.93 (0.82-1.07)	0.87 (0.76-0.99)	0.01
Nondairy calcium
Median intake, mg/d	202	260	303	378
Cases/non-cases	562/3,262	625/3,277	615/3,709	641/4,157
Model 1†	1.00	1.01 (0.88-1.15)	0.87 (0.76-1.00)	0.89 (0.78-1.01)	0.02
Model 2‡	1.00	1.03 (0.90-1.17)	0.89 (0.78-1.02)	0.89 (0.78-1.01)	0.02
Model 3**	1.00	1.11 (0.96-1.30)	1.01 (0.85-1.21)	1.06 (0.85-1.30)	0.81
Model 4††	1.00	1.04 (0.91-1.19)	0.91 (0.79-1.05)	0.92 (0.79-1.07)	0.14

^*Linear trend was tested by treating the median values of quartiles or frequency of milk intake as a continuous variable

^†Multivariable model 1: adjusted for age, sex, dialect, year of interview, educational level, and marriage status;

^‡Multivariable model 2: further adjusted for body mass index, physical activity, smoking status, alcohol use, baseline history of self-reported hypertension, diabetes, heart attack, and stroke, history of cancer, sleep status, and total energy intake;

^§Multivariable model 3: further adjusted for red meat, poultry, fish, vegetables, fruits, tea, coffee, and soda;

^**Multivariable model 4: model 2 plus vegetable-fruit-soy (VFS) dietary pattern.