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. 2019 Dec 2;16:246. doi: 10.1186/s12974-019-1649-3

Fig. 10.

Fig. 10

Effect of H89 on PAP-mediated microglial inactivation and CREB phosphorylation in the brains of MPTP-injected mice. a Immunohistochemical staining for Iba-1 and quantification of the number of Iba-1-positive microglia in the substantia nigra of MPTP-injected mice (each group n = 6–7). b The p-CREB levels in microglia were measured by immunofluorescence staining. The white arrows indicate cells positive for both OX42 and p-CREB. *p < 0.05, control vs. MPTP-treated group; #p < 0.05, MPTP vs. MPTP+PAP-treated group; ##p < 0.05, MPTP+PAP vs. MPTP+PAP+H89 group