Table 1:

Intracellular targets in the post-translational modifications associated with endogenous negative inhibition of NLRP3 inflammasome priming or activation phases.

Post-translational Modification Target	Phase of NLRP3 Inflammasome affected	References
(IKK)α	Priming via phosphorylation	87
PKA	Activation via phosphorylation	91–93
PTPN22	Activation via dephosphorylation	96
TRIM31	Activation via ubiquitination	88
ARIH2	Activation via ubiquitination	89
MARCH17	Activation via ubiquitination	95