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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Curr Opin Genet Dev. 2019 Aug 26;58-59:49–54. doi: 10.1016/j.gde.2019.07.011

Figure 2: Mechanisms by which gene conversion generates genetic novelty.

Figure 2:

A) The black and green lines represent nonallelic loci, the yellow arrowheads represent a repeated sequence and the blue box represents a gene. A DNA DSB in the green locus is repaired by copying sequence from the black locus, including the blue gene. The recombination event was seeded by homology shared between the yellow arrows. B) The blue boxes represent members of a gene family. Over time, the red variant can spread to all members of the blue gene family via gene conversion. C) The blue, red, and light blue boxes represent diverged members of a gene family. Over time, gene conversion can shuffle the variation between members of the family to generate novel alleles.