Table 4.
A multivariate permutation test (MPT), a combined test of all three univariate tests, was performed on the DWI measurements.
| Time | ADC | D | f | Combined | |||
|---|---|---|---|---|---|---|---|
| Median (IQR) | P-value | Median (IQR) | P-value | Median (IQR) | P-value | P-value (MPT) | |
| w5 | 1.02 (0.23) | 0.5412 | 1.03 (0.26) | 0.4900 | 0.84 (0.39) | 0.1232 | 0.3324 |
| w9 | 0.97 (0.19) | 0.8040 | 1.01 (0.28) | 0.7197 | 0.86 (0.51) | 0.2293 | 0.6039 |
The null hypothesis was that all three null hypotheses for the univariate tests hold and the alternative hypothesis was that at least one of the null hypotheses was not true. PMT showed no significant differences in the DWI parameters between baseline and follow-up Scan 1 and 2.