Fig. 4.

Islet Function before and after transplantation. (a) Insulin secretion by encapsulated islets prior to implantation. (b) Insulin secretion by retrieved encapsulated islets 90 days after implantation. (c) Glucose stimulation index (GSI) for encapsulated islets prior to transplantation and following retrieval. The GSI is defined as a ratio of the maximum amount of insulin secreted during the high glucose period over the average amount of insulin secreted over low glucose period. The GSI for retrieved islets was not significantly different from that for the pre-transplant group (2.75 ± 0.68 vs. 4.11 ± 0.48 respectively, p = 0.13). Error bars represent mean ± SEM, N = 5