Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Sep 16;121(8):699–709. doi: 10.1038/s41416-019-0571-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — Gene structure and phylogenetic conservative analysis of COMMD6. a Chromosome location of COMMD6 (Highlighted in red line) was shown in top panel. Gene structure of COMMD6 was shown in median panel. Black box represents exons and grey box represents introns. Protein structure of COMMD6 was shown in bottom panel (Black box represents COMMD domain). b Phylogenetic tree of Homo sapiens COMMD family proteins including COMMD6 (Highlighted in red frame). The tree is drawn to scale, with branch lengths in the same units as those of the evolutionary distances used to infer the phylogenetic tree. The evolutionary distances were computed using the Poisson correction method and are in the units of the number of amino acid substitutions per site. c Alignments analysis of COMMD6 protein sequence among Homo sapiens (UniProtKB-Q7Z4G1), Mus musculus (UniProtKB-Q3V4B5), Sus scrofa (UniProtKB-A0A286ZXE0), Felis catus (UniProtKB-M3WUJ0), Bos taurus (UniProtKB-Q2KIY) and Ovis aries (UniProtKB-W5Q264). The degree of conservation of each amino acid residue among these sequences is indicated green (100% conserved), yellow (75% conserved) and blue (50% conserved)