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. 2019 Dec 3;17(Suppl 2):73. doi: 10.1186/s12969-019-0373-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 (abstract A63). — Double Immunofluorescence Staining for vWF and Collagen III in the Skin of a Patient with LS. Cuts of the reticular dermis are shown at different magnifications. There is increased collagen expression (green) throughout the reticular dermis that diffusely co-localize with increased expression of vWF (red). Vessels (arrow) stain at a higher intensity due to the presence of vWF in the subendothelium. A superficial and deep perivascular, and interstitial inflammatory cell infiltrate (blue) is also found co-localizing with vWF in areas of higher vWF expression