Table 1.
Demographic and clinical characteristics of gingivo-buccal oral squamous cell carcinoma patients included in this study
| Clinical characteristics | Methylation discovery set | Methylation validation set | Expression discovery set | Expression validation set |
|---|---|---|---|---|
| (n = 43) | (n = 44) | (n = 36) | (n = 36) | |
| Age (in years) | ||||
| Range | 26–74 | 26–65 | 26–70 | 32–72 |
| Mean | 50.81 ± 12.77 | 48.7 ± 9.9 | 50.33 ± 11.19 | 49.08 ± 10.43 |
| < 40 | 9 | 7 | 7 | 5 |
| 40–45 | 7 | 11 | 6 | 12 |
| 46–50 | 6 | 8 | 4 | 6 |
| 51–55 | 3 | 7 | 7 | 4 |
| 56–60 | 5 | 5 | 5 | 1 |
| > 60 | 13 | 6 | 7 | 8 |
| Gender | ||||
| Male | 39 | 36 | 31 | 28 |
| Female | 4 | 8 | 5 | 8 |
| Risk-habit | ||||
| Tobacco chewing | 16 | 22 | 17 | 18 |
| Tobacco chewing and (smoking and/or alcohol) | 25 | 17 | 15 | 13 |
| Smoking and/or alcohol | 1 | 4 | 3 | 4 |
| None | 1 | 1 | 1 | 1 |
| Tumour stage* | ||||
| T1 | 0 | 10 | 10 | 8 |
| T2 | 12 | 13 | 11 | 10 |
| T3 | 4 | 0 | 1 | 1 |
| T4 | 27 | 21 | 14 | 17 |
| Lymph node invasion* | ||||
| N0 | 18 | 22 | 17 | 14 |
| N+ | 25 | 22 | 19 | 22 |
*All patients were M0 (no metastasis) at first presentation when tissue samples were collected for analysis