Table 3.
Univariate and multivariate analysis of prognostics factors for overall survival in HCC patients after curative resection
| Univariate | Multivariate | ||||
|---|---|---|---|---|---|
| Variable | Comparison | HR (95%CI) | P value | HR (95%CI) | P value |
| Age (years) | ≥65 vs. < 65 | 1.311 (0.857–2.006) | 0.212 | ||
| Gender | Male vs. Female | 0.990 (0.583–1.682) | 0.971 | ||
| Total bilirubin (mg/dl) | Per 1 unit increase | 0.986 (0.888–1.095) | 0.787 | ||
| Albumin (mg/dl) | Per 1 unit increase | 1.001 (0.692–1.447) | 0.998 | ||
| Platelet (× 109/L) | < 150 vs. ≥150 | 1.028 (0.675–1.566) | 0.897 | ||
| AFP (ng/mL) | ≥200 vs. < 200 | 2.012 (1.288–3.143) | 0.002 | ||
| uPA (ng/ml) | ≥1 vs. < 1 | 1.968 (1.271–3.049) | 0.002 | 1.848 (1.191–2.867) | 0.006 |
| Liver cirrhosis | Yes vs. No | 1.039 (0.680–1.588) | 0.859 | ||
| Tumor size (cm) | ≥5 vs. < 5 | 2.402 (1.575–3.663) | < 0.001 | ||
| Vascular invasion | Yes vs. No | 3.812 (2.268–6.407) | < 0.001 | 2.940 (1.655–5.224) | < 0.001 |
| Pathology stage | III + IV vs. I + II | 4.980 (3.226–7.687) | < 0.001 | 3.517 (2.208–5.600) | < 0.001 |