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Hsp60 knockdown inhibits IL-8 expression and release. a Estimation of IL-8 in serum of mock and Hsp60 knockdown PC-3 cell xenografts using ELISA. b Immunohistochemistry of IL-8 in tumour sections of mock and Hsp60 knock down xenografts. c Schematic diagram of Hsp60-IL-8 axis and its role in apoptosis resistance. Data are mean ± SD (n = 5). *p < 0.05 vs controls
