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. 2019 Dec 2;16:119. doi: 10.1186/s12966-019-0855-9

Table 2.

Intervention effects on frailty score during the 6-month study period

Mean ± SD Difference in difference: change from baseline in each intervention group minus change from baseline in control group (95% CI) p for groups × time interaction p for groups p for time
Outcome Control Exercise Nutrition Combination Exercise Nutrition Combination
Frailty score (scores) n 80 79 83 77 <  0.001 0.402 <  0.001
Baseline 1.5 ± 0.6 1.6 ± 0.8 1.7 ± 0.8 1.5 ± 0.7
1 month 1.4 ± 0.8 1.4 ± 0.8 1.7 ± 0.9 1.3 ± 0.8 −0.06 (−0.24, 0.11) 0.10 (− 0.08, 0.28) − 0.07(− 0.25, 0.11)
3 months 1.3 ± 0.8 1.5 ± 0.9 1.4 ± 0.9 1.3 ± 0.7 0.11 (− 0.07, 0.29) − 0.06 (− 0.24, 0.11) − 0.03 (− 0.21, 0.15)
6 months 1.4 ± 0.9 1.3 ± 0.9 1.3 ± 0.9 1.1 ± 0.8 − 0.23 (− 0.41, − 0.05)a −0.28 (− 0.46, − 0.11)a −0.34 (− 0.52, − 0.16)a

CI confidence interval; aPairwise comparisons (interventions vs. control) were significant at the post hoc significance level of 0.017

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