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. 2019 Dec 3;20:920. doi: 10.1186/s12864-019-6322-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Molecular model of regulatory modules that shape cellular differentiation during gametocytogenesis. Specific regulatory events are mapped out over the extended gametocyte development of P. falciparum parasites. Molecular regulators are highlighted in red while specific events or epigenetic marks are shown in black. Colored blocks indicate the span of specific phases of transcript abundance, with dotted lines indicating transition points in gametocyte development and grey triangles indicate the timing of repressive mechanisms in gametocyte development. Parasite drawings were modified from freely available images (https://smart.servier.com/), under a Creative Commons Attribution 3.0 Unported Licence