Figure 3.
FGF21-stimulated lipid uptake in iBAT. (A) TAG and (B) G3P content of iBAT, sWAT, and vWAT and (C) lipid uptake in iBAT, sWAT, and vWAT in response to treatment with FGF21 or vehicle or in pair-fed controls (PF). Data are mean ± SEM. N = 4/group. Statistical analyses conducted using one-way ANOVA with Tukey's multiple comparison test. *p < 0.05. (E) LPL, (F) CD36, (G) FATP1, and (H) PPARα expression in iBAT in response to treatment with FGF21 (vs saline controls). N = 4/group. Data are mean ± SEM. N = 4/group. Statistical analyses conducted using one-way ANOVA with Tukey's multiple comparison test. *p < 0.05.