Table 1.
Compound name | Screen category | Class | Approved (e.g. FDA) | Rule of 5 |
---|---|---|---|---|
Astemizole | 1 | Anti-histamine | Yesa | No |
Terfenadine | 1 | Anti-histamine | Yesa | No |
Simvastatin | 2 | Lipid-lowering | Yes | Yes |
Sulconazole | 2 | Anti-infective | Yes | Yes |
Budesonide | 2 | Corticosteroid | Yes | Yes |
Halcinonide | 2 | Corticosteroid | Yes | Yes |
Mometasone | 2 | Corticosteroid | Yes | Yes |
Menadione | 2 | Vitamin | Yesb | Yes |
Ebselen | 2 | Other | No | Yes |
H-7 | 2 | Other | No | Not available |
Proadifen | 2 | Other | No | Yes |
Digoxin | 2 | Cardio-vascular | Yes | Yes |
Strophanthidin | 2 | Cardio-vascular | No | Yes |
Ouabain | 2 | Cardio-vascular | No | Yes |
aWithdrawn from the market
bDiscontinued from the market