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. 2019 Oct 31;15:223–233. doi: 10.1016/j.omto.2019.10.006

Figure 1.

Figure 1

FOXO3a Protein Is Downregulated in GC and Functional Experiments

(A) Western blotting analysis (a) of FOXO3a expression in tumor tissues and adjacent normal tissues (n = 8) and the corresponding quantitative analysis (b). (B) qRT-PCR analysis of FOXO3a mRNA levels in tumor tissues and adjacent normal tissues (n = 8). (C) Western blotting analysis of FOXO3a expression in the OE group and KD group and the corresponding quantitative analysis are shown. (D) qRT-PCR analysis of FOXO3a mRNA in the OE group and KD group. (E) EdU assay revealed that overexpression of FOXO3a inhibited the proliferation of HUVECs (n = 3). (F) Quantitative data of (E) (n = 3). (G) Wound healing assay showing that FOXO3a inhibited the migration of HUVECs; the corresponding quantitative analysis is also shown (n = 3). (H) FOXO3a suppressed the ability of ring formation in HUVECs, and the corresponding quantitative analysis is shown (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001.