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. 2019 Oct 31;15:223–233. doi: 10.1016/j.omto.2019.10.006

Figure 4.

Figure 4

MiR-155 Directly Promotes Angiogenesis InVitro

(A) Western blotting analysis of FOXO3a expression in HUVECs transfected with NC mimics, miR-155 mimics, NC inhibitors, and miR-155 inhibitors, as well as the corresponding quantitative analysis (n = 3). (B) qRT-PCR analysis of FOXO3a mRNA levels in the above transfected HUVECs (n = 3). (C) EdU assays showing that miR-155 enhanced the proliferation of HUVECs (n = 3). (D) Quantification of data in (C) (n = 3). (E) Wound healing assay showing that miR-155 promoted the migration of HUVECs (n = 3). (F) Quantitative analysis of data in (E) (n = 3). (G) Ring formation in HUVECs transfected with miR-155 mimics was enhanced (n = 3). (H) Quantification of data in (G) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001.