Figure 5.

The Restoration Experiments

(A) Schematic description of the experimental design. (B) Western blotting analysis of FOXO3a expression in the rescue experiment and the corresponding quantitative analysis (n = 3). (C) EdU assays demonstrated that the restoration of FOXO3a content enhanced the function of miR-155 in promoting the proliferation (n = 3). (D) Quantification of data in (C) (n = 3). (E) Wound healing assay revealed that the restoration of FOXO3a content enhanced the function of miR-155 in promoting the migration (n = 3). (F) Quantitative analysis of data in (E) (n = 3). (G) The ability of ring formation in HUVECs with restoration of FOXO3a content was enhanced (n = 3). (H) Quantification of data in (G) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001.