Table 3.
Unappreciated CD45+/CK+ Cells in Prior Publications
| Study | Cancer site | Explanation for CD45+/CK+ cells | Relevant findings |
|---|---|---|---|
| Zhang et al18 | PDAC | Unknown | ND |
| Toyoshima et al127 | Gastric | Unknown | Increased tumorigenicity |
| de Wit et al126 | NSCLC | Unknown | ND |
| Nel et al129 | NSCLC | Unknown | ND |
| Stott et al133 | NSCLC, prostate | Trogocytosis | CD45+/CK+ more prevalent than CTCs |
| Sajay et al128 | NSCLC, breast | Unknown | ND |
| Takao and Takeda132 | NSCLC, breast | False positive | ND |
| Lustberg et al131 | HNSCC, breast | Unknown | ND |
| Lustberg et al130 | Breast | Artifact | ND |
| Riethdorf et al134 | Breast | Artifact | ND |
| Allan et al135 | Breast | Artifact | ND |
HNSCC, head and neck squamous cell carcinoma; ND, not determined; NSCLC, non–small-cell lung cancer.